| Los Barrios to Southern Pines (North Carolina) | 4,039.92 mi (6,501.63 km) |
| Los Barrios to Southfield (Michigan) | 4,031.71 mi (6,488.41 km) |
| Los Barrios to Southgate (Michigan) | 4,036.20 mi (6,495.63 km) |
| Los Barrios to Southlake (Texas) | 5,006.20 mi (8,056.70 km) |
| Los Barrios to Spanaway (Washington) | 5,487.73 mi (8,831.65 km) |
| Los Barrios to Spanish Fork (Utah) | 5,386.60 mi (8,668.90 km) |
| Los Barrios to Spanish Lake (Missouri) | 4,468.92 mi (7,192.03 km) |
| Los Barrios to Spanish Springs (Nevada) | 5,733.50 mi (9,227.18 km) |
| Los Barrios to Sparks (Nevada) | 5,739.20 mi (9,236.36 km) |
| Los Barrios to Spartanburg (South Carolina) | 4,176.36 mi (6,721.20 km) |
| Los Barrios to Spearfish (South Dakota) | 4,885.83 mi (7,862.98 km) |
| Los Barrios to Speedway (Indiana) | 4,248.24 mi (6,836.88 km) |
| Los Barrios to Spencer (Iowa) | 4,558.46 mi (7,336.14 km) |
| Los Barrios to Spokane (Washington) | 5,286.42 mi (8,507.68 km) |
| Los Barrios to Spokane Valley (Washington) | 5,279.51 mi (8,496.55 km) |
