| Los Angeles to Southern Pines (North Carolina) | 2,203.72 mi (3,546.54 km) |
| Los Angeles to Southfield (Michigan) | 1,975.60 mi (3,179.42 km) |
| Los Angeles to Southgate (Michigan) | 1,976.77 mi (3,181.31 km) |
| Los Angeles to Southlake (Texas) | 1,224.64 mi (1,970.87 km) |
| Los Angeles to Spanaway (Washington) | 921.17 mi (1,482.47 km) |
| Los Angeles to Spanish Fork (Utah) | 556.97 mi (896.36 km) |
| Los Angeles to Spanish Lake (Missouri) | 1,593.45 mi (2,564.41 km) |
| Los Angeles to Spanish Springs (Nevada) | 389.25 mi (626.45 km) |
| Los Angeles to Sparks (Nevada) | 384.09 mi (618.13 km) |
| Los Angeles to Spartanburg (South Carolina) | 2,065.78 mi (3,324.56 km) |
| Los Angeles to Spearfish (South Dakota) | 1,056.55 mi (1,700.35 km) |
| Los Angeles to Speedway (Indiana) | 1,808.14 mi (2,909.92 km) |
| Los Angeles to Spencer (Iowa) | 1,395.26 mi (2,245.45 km) |
| Los Angeles to Spokane (Washington) | 937.78 mi (1,509.21 km) |
| Los Angeles to Spokane Valley (Washington) | 938.08 mi (1,509.69 km) |
