| Lockport to Enterprise (Nevada) | 1,507.54 mi (2,426.15 km) |
| Lockport to Enumclaw (Washington) | 1,706.38 mi (2,746.16 km) |
| Lockport to Ephrata (Pennsylvania) | 625.99 mi (1,007.43 km) |
| Lockport to Erie (Colorado) | 894.45 mi (1,439.48 km) |
| Lockport to Erie (Pennsylvania) | 410.91 mi (661.29 km) |
| Lockport to Erlanger (Kentucky) | 254.29 mi (409.24 km) |
| Lockport to Escanaba (Michigan) | 291.03 mi (468.37 km) |
| Lockport to Escondido (California) | 1,688.81 mi (2,717.87 km) |
| Lockport to Española (New Mexico) | 1,042.74 mi (1,678.13 km) |
| Lockport to Essex (Maryland) | 628.76 mi (1,011.89 km) |
| Lockport to Essex Junction (Vermont) | 778.14 mi (1,252.30 km) |
| Lockport to Estelle (Louisiana) | 819.78 mi (1,319.30 km) |
| Lockport to Estero (Florida) | 1,106.02 mi (1,779.97 km) |
| Lockport to Euclid (Ohio) | 336.35 mi (541.31 km) |
| Lockport to Eufaula (Alabama) | 687.46 mi (1,106.36 km) |
