| Littleport to Southern Pines (North Carolina) | 3,932.20 mi (6,328.27 km) |
| Littleport to Southfield (Michigan) | 3,740.74 mi (6,020.13 km) |
| Littleport to Southgate (Michigan) | 3,751.14 mi (6,036.88 km) |
| Littleport to Southlake (Texas) | 4,739.40 mi (7,627.32 km) |
| Littleport to Spanaway (Washington) | 4,775.20 mi (7,684.94 km) |
| Littleport to Spanish Fork (Utah) | 4,859.09 mi (7,819.95 km) |
| Littleport to Spanish Lake (Missouri) | 4,179.99 mi (6,727.04 km) |
| Littleport to Spanish Springs (Nevada) | 5,129.39 mi (8,254.95 km) |
| Littleport to Sparks (Nevada) | 5,135.56 mi (8,264.88 km) |
| Littleport to Spartanburg (South Carolina) | 4,045.73 mi (6,510.97 km) |
| Littleport to Spearfish (South Dakota) | 4,372.31 mi (7,036.55 km) |
| Littleport to Speedway (Indiana) | 3,980.72 mi (6,406.35 km) |
| Littleport to Spencer (Iowa) | 4,145.83 mi (6,672.07 km) |
| Littleport to Spokane (Washington) | 4,610.23 mi (7,419.45 km) |
| Littleport to Spokane Valley (Washington) | 4,605.06 mi (7,411.12 km) |
