| Little Rock to Seymour (Tennessee) | 490.75 mi (789.79 km) |
| Little Rock to Shady Hills (Florida) | 723.47 mi (1,164.32 km) |
| Little Rock to Shafter (California) | 1,513.60 mi (2,435.91 km) |
| Little Rock to Shaker Heights (Ohio) | 749.16 mi (1,205.66 km) |
| Little Rock to Shakopee (Minnesota) | 696.83 mi (1,121.45 km) |
| Little Rock to Sharon (Pennsylvania) | 785.77 mi (1,264.58 km) |
| Little Rock to Sharonville (Ohio) | 539.63 mi (868.45 km) |
| Little Rock to Shasta Lake (California) | 1,682.91 mi (2,708.39 km) |
| Little Rock to Shawnee (Kansas) | 325.85 mi (524.41 km) |
| Little Rock to Shawnee (Oklahoma) | 264.18 mi (425.15 km) |
| Little Rock to Sheboygan (Wisconsin) | 669.96 mi (1,078.20 km) |
| Little Rock to Shelby (North Carolina) | 612.85 mi (986.29 km) |
| Little Rock to Shelbyville (Indiana) | 491.41 mi (790.85 km) |
| Little Rock to Shelbyville (Kentucky) | 463.19 mi (745.43 km) |
| Little Rock to Shelbyville (Tennessee) | 338.00 mi (543.96 km) |
