| Little Rock to Santa Rosa (California) | 1,695.45 mi (2,728.56 km) |
| Little Rock to Santaquin (Utah) | 1,124.64 mi (1,809.94 km) |
| Little Rock to Santee (California) | 1,416.50 mi (2,279.64 km) |
| Little Rock to Sapulpa (Oklahoma) | 228.74 mi (368.11 km) |
| Little Rock to Saraland (Alabama) | 364.52 mi (586.64 km) |
| Little Rock to Sarasota (Florida) | 772.61 mi (1,243.40 km) |
| Little Rock to Sarasota Springs (Florida) | 777.09 mi (1,250.60 km) |
| Little Rock to Saratoga (California) | 1,660.93 mi (2,673.00 km) |
| Little Rock to Saratoga Springs (New York) | 1,149.69 mi (1,850.24 km) |
| Little Rock to Saratoga Springs (Utah) | 1,136.78 mi (1,829.47 km) |
| Little Rock to Sartell (Minnesota) | 758.99 mi (1,221.47 km) |
| Little Rock to Satellite Beach (Florida) | 826.56 mi (1,330.22 km) |
| Little Rock to Sauk Rapids (Minnesota) | 757.12 mi (1,218.47 km) |
| Little Rock to Sault Ste. Marie (Michigan) | 912.77 mi (1,468.97 km) |
| Little Rock to Savage (Minnesota) | 694.97 mi (1,118.45 km) |
