| Little Rock to Olympia Heights (Florida) | 948.19 mi (1,525.96 km) |
| Little Rock to Omaha (Nebraska) | 494.33 mi (795.54 km) |
| Little Rock to On Top of the World Designated Place (Florida) | 706.25 mi (1,136.59 km) |
| Little Rock to Onalaska (Wisconsin) | 636.04 mi (1,023.61 km) |
| Little Rock to Oneida (New York) | 1,064.13 mi (1,712.56 km) |
| Little Rock to Oneonta (New York) | 1,072.74 mi (1,726.41 km) |
| Little Rock to Ontario (California) | 1,436.73 mi (2,312.19 km) |
| Little Rock to Ontario (Oregon) | 1,455.83 mi (2,342.94 km) |
| Little Rock to Opa-locka (Florida) | 943.61 mi (1,518.60 km) |
| Little Rock to Opelika (Alabama) | 425.78 mi (685.23 km) |
| Little Rock to Opelousas (Louisiana) | 290.66 mi (467.78 km) |
| Little Rock to Orange (California) | 1,451.57 mi (2,336.07 km) |
| Little Rock to Orange (Texas) | 328.38 mi (528.48 km) |
| Little Rock to Orange City (Florida) | 762.37 mi (1,226.91 km) |
| Little Rock to Orangeburg (South Carolina) | 662.47 mi (1,066.14 km) |
