| Little Rock to Elyria (Ohio) | 721.77 mi (1,161.57 km) |
| Little Rock to Emeryville (California) | 1,673.90 mi (2,693.89 km) |
| Little Rock to Emmaus (Pennsylvania) | 1,003.95 mi (1,615.71 km) |
| Little Rock to Emporia (Kansas) | 331.38 mi (533.30 km) |
| Little Rock to Encinitas (California) | 1,429.41 mi (2,300.42 km) |
| Little Rock to Endicott (New York) | 1,016.12 mi (1,635.28 km) |
| Little Rock to Endwell (New York) | 1,018.66 mi (1,639.38 km) |
| Little Rock to Englewood (Colorado) | 773.25 mi (1,244.42 km) |
| Little Rock to Englewood (Florida) | 798.69 mi (1,285.37 km) |
| Little Rock to Englewood (New Jersey) | 1,087.49 mi (1,750.14 km) |
| Little Rock to Englewood (Ohio) | 566.92 mi (912.37 km) |
| Little Rock to Enid (Oklahoma) | 330.80 mi (532.36 km) |
| Little Rock to Ennis (Texas) | 296.92 mi (477.85 km) |
| Little Rock to Ensley (Florida) | 414.29 mi (666.73 km) |
| Little Rock to Enterprise (Alabama) | 444.14 mi (714.78 km) |
