| Little Chute to Southern Pines (North Carolina) | 786.09 mi (1,265.09 km) |
| Little Chute to Southfield (Michigan) | 283.27 mi (455.87 km) |
| Little Chute to Southgate (Michigan) | 294.95 mi (474.67 km) |
| Little Chute to Southlake (Texas) | 915.59 mi (1,473.50 km) |
| Little Chute to Spanaway (Washington) | 1,643.98 mi (2,645.73 km) |
| Little Chute to Spanish Fork (Utah) | 1,223.52 mi (1,969.06 km) |
| Little Chute to Spanish Lake (Missouri) | 392.46 mi (631.60 km) |
| Little Chute to Spanish Springs (Nevada) | 1,631.39 mi (2,625.47 km) |
| Little Chute to Sparks (Nevada) | 1,635.83 mi (2,632.61 km) |
| Little Chute to Spartanburg (South Carolina) | 729.43 mi (1,173.90 km) |
| Little Chute to Spearfish (South Dakota) | 764.00 mi (1,229.54 km) |
| Little Chute to Speedway (Indiana) | 328.37 mi (528.47 km) |
| Little Chute to Spencer (Iowa) | 350.11 mi (563.46 km) |
| Little Chute to Spokane (Washington) | 1,408.55 mi (2,266.84 km) |
| Little Chute to Spokane Valley (Washington) | 1,399.33 mi (2,252.00 km) |
