| Little Chute to Enterprise (Nevada) | 1,523.18 mi (2,451.32 km) |
| Little Chute to Enumclaw (Washington) | 1,623.00 mi (2,611.97 km) |
| Little Chute to Ephrata (Pennsylvania) | 681.94 mi (1,097.48 km) |
| Little Chute to Erie (Colorado) | 903.24 mi (1,453.63 km) |
| Little Chute to Erie (Pennsylvania) | 441.45 mi (710.45 km) |
| Little Chute to Erlanger (Kentucky) | 412.49 mi (663.84 km) |
| Little Chute to Escanaba (Michigan) | 117.25 mi (188.70 km) |
| Little Chute to Escondido (California) | 1,718.90 mi (2,766.30 km) |
| Little Chute to Española (New Mexico) | 1,094.82 mi (1,761.94 km) |
| Little Chute to Essex (Maryland) | 701.15 mi (1,128.40 km) |
| Little Chute to Essex Junction (Vermont) | 749.85 mi (1,206.77 km) |
| Little Chute to Estelle (Louisiana) | 1,002.87 mi (1,613.96 km) |
| Little Chute to Estero (Florida) | 1,286.73 mi (2,070.80 km) |
| Little Chute to Euclid (Ohio) | 391.20 mi (629.57 km) |
| Little Chute to Eufaula (Alabama) | 872.41 mi (1,404.00 km) |
