| Lewes to Smyrna (Delaware) | 3,608.35 mi (5,807.08 km) |
| Lewes to Smyrna (Georgia) | 4,226.36 mi (6,801.67 km) |
| Lewes to Smyrna (Tennessee) | 4,207.12 mi (6,770.71 km) |
| Lewes to Snellville (Georgia) | 4,205.57 mi (6,768.22 km) |
| Lewes to Snoqualmie (Washington) | 4,813.98 mi (7,747.34 km) |
| Lewes to Snyder (Texas) | 4,934.58 mi (7,941.44 km) |
| Lewes to Socastee (South Carolina) | 4,005.69 mi (6,446.53 km) |
| Lewes to Socorro (Texas) | 5,191.90 mi (8,355.55 km) |
| Lewes to Soddy-Daisy (Tennessee) | 4,186.37 mi (6,737.31 km) |
| Lewes to Solana Beach (California) | 5,502.07 mi (8,854.73 km) |
| Lewes to Soledad (California) | 5,434.61 mi (8,746.17 km) |
| Lewes to Solon (Ohio) | 3,753.14 mi (6,040.09 km) |
| Lewes to Somers Point (New Jersey) | 3,565.84 mi (5,738.67 km) |
| Lewes to Somerset (Kentucky) | 4,076.93 mi (6,561.18 km) |
| Lewes to Somerset (New Jersey) | 3,510.00 mi (5,648.80 km) |
