| Lewes to Silver Firs (Washington) | 4,803.21 mi (7,730.02 km) |
| Lewes to Silver Spring (Maryland) | 3,679.46 mi (5,921.52 km) |
| Lewes to Silver Springs Shores (Florida) | 4,353.26 mi (7,005.89 km) |
| Lewes to Silverdale (Washington) | 4,828.48 mi (7,770.69 km) |
| Lewes to Silverton (Oregon) | 4,983.39 mi (8,019.99 km) |
| Lewes to Simi Valley (California) | 5,478.28 mi (8,816.43 km) |
| Lewes to Simpsonville (South Carolina) | 4,091.83 mi (6,585.16 km) |
| Lewes to Sioux City (Iowa) | 4,271.62 mi (6,874.50 km) |
| Lewes to Sioux Falls (South Dakota) | 4,233.34 mi (6,812.90 km) |
| Lewes to Skokie (Illinois) | 3,970.34 mi (6,389.64 km) |
| Lewes to Sleepy Hollow (New York) | 3,459.18 mi (5,567.02 km) |
| Lewes to Slidell (Louisiana) | 4,618.55 mi (7,432.83 km) |
| Lewes to Smithfield (North Carolina) | 3,892.74 mi (6,264.76 km) |
| Lewes to Smithfield (Utah) | 4,834.36 mi (7,780.15 km) |
| Lewes to Smithville (Missouri) | 4,355.84 mi (7,010.05 km) |
