| Lewes to Scottsboro (Alabama) | 4,251.45 mi (6,842.05 km) |
| Lewes to Scottsdale (Arizona) | 5,280.76 mi (8,498.56 km) |
| Lewes to Scranton (Pennsylvania) | 3,519.47 mi (5,664.04 km) |
| Lewes to Seabrook (Maryland) | 3,673.43 mi (5,911.82 km) |
| Lewes to Seabrook (Texas) | 4,867.23 mi (7,833.04 km) |
| Lewes to Seaford (New York) | 3,461.56 mi (5,570.84 km) |
| Lewes to Seagoville (Texas) | 4,769.45 mi (7,675.68 km) |
| Lewes to Seal Beach (California) | 5,485.56 mi (8,828.16 km) |
| Lewes to Searcy (Arkansas) | 4,450.29 mi (7,162.05 km) |
| Lewes to Seaside (California) | 5,438.78 mi (8,752.88 km) |
| Lewes to SeaTac (Washington) | 4,830.96 mi (7,774.68 km) |
| Lewes to Seattle (Washington) | 4,821.60 mi (7,759.61 km) |
| Lewes to Sebastian (Florida) | 4,353.73 mi (7,006.65 km) |
| Lewes to Sebring (Florida) | 4,410.28 mi (7,097.66 km) |
| Lewes to Secaucus (New Jersey) | 3,480.43 mi (5,601.20 km) |
