| Lewes to Olympia Heights (Florida) | 4,449.98 mi (7,161.55 km) |
| Lewes to Omaha (Nebraska) | 4,319.37 mi (6,951.36 km) |
| Lewes to On Top of the World Designated Place (Florida) | 4,365.09 mi (7,024.94 km) |
| Lewes to Onalaska (Wisconsin) | 4,015.77 mi (6,462.75 km) |
| Lewes to Oneida (New York) | 3,449.00 mi (5,550.63 km) |
| Lewes to Oneonta (New York) | 3,450.79 mi (5,553.52 km) |
| Lewes to Ontario (California) | 5,454.20 mi (8,777.69 km) |
| Lewes to Ontario (Oregon) | 4,873.42 mi (7,843.01 km) |
| Lewes to Opa-locka (Florida) | 4,437.60 mi (7,141.63 km) |
| Lewes to Opelika (Alabama) | 4,320.03 mi (6,952.41 km) |
| Lewes to Opelousas (Louisiana) | 4,700.20 mi (7,564.25 km) |
| Lewes to Orange (California) | 5,474.61 mi (8,810.53 km) |
| Lewes to Orange (Texas) | 4,788.44 mi (7,706.25 km) |
| Lewes to Orange City (Florida) | 4,331.20 mi (6,970.39 km) |
| Lewes to Orangeburg (South Carolina) | 4,092.75 mi (6,586.65 km) |
