| Cities | Distance |
|---|---|
| Lewes to Shotley Bridge | 286.84 mi (461.63 km) |
| Lewes to Shrewsbury | 173.22 mi (278.78 km) |
| Lewes to Sidcup | 38.31 mi (61.66 km) |
| Lewes to Sidmouth | 142.65 mi (229.57 km) |
| Lewes to Sileby | 136.86 mi (220.25 km) |
| Lewes to Sittingbourne | 45.07 mi (72.54 km) |
| Lewes to Skegness | 157.40 mi (253.31 km) |
| Lewes to Skelmersdale | 219.27 mi (352.88 km) |
| Lewes to Skipton | 229.80 mi (369.83 km) |
| Lewes to Sleaford | 147.68 mi (237.67 km) |
| Lewes to Slough | 50.91 mi (81.93 km) |
| Lewes to Small Heath | 135.76 mi (218.49 km) |
| Lewes to Smethwick | 140.35 mi (225.87 km) |
| Lewes to Snaresbrook | 49.22 mi (79.20 km) |
| Lewes to Snodland | 36.57 mi (58.85 km) |