| Leighton Buzzard to Southern Pines (North Carolina) | 3,903.28 mi (6,281.72 km) |
| Leighton Buzzard to Southfield (Michigan) | 3,719.55 mi (5,986.04 km) |
| Leighton Buzzard to Southgate (Michigan) | 3,729.71 mi (6,002.38 km) |
| Leighton Buzzard to Southlake (Texas) | 4,719.36 mi (7,595.07 km) |
| Leighton Buzzard to Spanaway (Washington) | 4,779.38 mi (7,691.68 km) |
| Leighton Buzzard to Spanish Fork (Utah) | 4,852.57 mi (7,809.46 km) |
| Leighton Buzzard to Spanish Lake (Missouri) | 4,159.79 mi (6,694.53 km) |
| Leighton Buzzard to Spanish Springs (Nevada) | 5,127.68 mi (8,252.20 km) |
| Leighton Buzzard to Sparks (Nevada) | 5,133.83 mi (8,262.10 km) |
| Leighton Buzzard to Spartanburg (South Carolina) | 4,018.05 mi (6,466.43 km) |
| Leighton Buzzard to Spearfish (South Dakota) | 4,364.05 mi (7,023.26 km) |
| Leighton Buzzard to Speedway (Indiana) | 3,959.03 mi (6,371.45 km) |
| Leighton Buzzard to Spencer (Iowa) | 4,131.69 mi (6,649.32 km) |
| Leighton Buzzard to Spokane (Washington) | 4,611.87 mi (7,422.09 km) |
| Leighton Buzzard to Spokane Valley (Washington) | 4,606.58 mi (7,413.58 km) |
