| Lehigh Acres to Southern Pines (North Carolina) | 607.44 mi (977.58 km) |
| Lehigh Acres to Southfield (Michigan) | 1,099.95 mi (1,770.20 km) |
| Lehigh Acres to Southgate (Michigan) | 1,080.99 mi (1,739.69 km) |
| Lehigh Acres to Southlake (Texas) | 1,026.74 mi (1,652.38 km) |
| Lehigh Acres to Spanaway (Washington) | 2,619.40 mi (4,215.51 km) |
| Lehigh Acres to Spanish Fork (Utah) | 1,953.00 mi (3,143.05 km) |
| Lehigh Acres to Spanish Lake (Missouri) | 976.62 mi (1,571.72 km) |
| Lehigh Acres to Spanish Springs (Nevada) | 2,356.15 mi (3,791.85 km) |
| Lehigh Acres to Sparks (Nevada) | 2,357.53 mi (3,794.07 km) |
| Lehigh Acres to Spartanburg (South Carolina) | 575.95 mi (926.90 km) |
| Lehigh Acres to Spearfish (South Dakota) | 1,743.94 mi (2,806.60 km) |
| Lehigh Acres to Speedway (Indiana) | 948.57 mi (1,526.57 km) |
| Lehigh Acres to Spencer (Iowa) | 1,371.50 mi (2,207.22 km) |
| Lehigh Acres to Spokane (Washington) | 2,415.77 mi (3,887.80 km) |
| Lehigh Acres to Spokane Valley (Washington) | 2,407.22 mi (3,874.05 km) |
