| Lehigh Acres to Security-Widefield (Colorado) | 1,575.37 mi (2,535.31 km) |
| Lehigh Acres to Sedalia (Missouri) | 1,071.88 mi (1,725.03 km) |
| Lehigh Acres to Sedro-Woolley (Washington) | 2,642.90 mi (4,253.33 km) |
| Lehigh Acres to Seguin (Texas) | 1,015.31 mi (1,633.99 km) |
| Lehigh Acres to Selden (New York) | 1,100.58 mi (1,771.22 km) |
| Lehigh Acres to Selma (Alabama) | 515.63 mi (829.82 km) |
| Lehigh Acres to Selma (California) | 2,321.66 mi (3,736.35 km) |
| Lehigh Acres to Selma (Texas) | 1,035.88 mi (1,667.08 km) |
| Lehigh Acres to Seminole (Florida) | 110.41 mi (177.68 km) |
| Lehigh Acres to Seven Hills (Ohio) | 1,020.39 mi (1,642.16 km) |
| Lehigh Acres to Seven Oaks (South Carolina) | 514.59 mi (828.15 km) |
| Lehigh Acres to Severn (Maryland) | 911.18 mi (1,466.41 km) |
| Lehigh Acres to Severna Park (Maryland) | 910.36 mi (1,465.09 km) |
| Lehigh Acres to Sevierville (Tennessee) | 650.86 mi (1,047.46 km) |
| Lehigh Acres to Seymour (Indiana) | 887.08 mi (1,427.61 km) |
