| League City to University Place (Washington) | 1,908.65 mi (3,071.67 km) |
| League City to Upland (California) | 1,359.25 mi (2,187.50 km) |
| League City to Upper Arlington (Ohio) | 996.75 mi (1,604.11 km) |
| League City to Upper Grand Lagoon (Florida) | 563.33 mi (906.59 km) |
| League City to Upper Montclair (New Jersey) | 1,411.99 mi (2,272.38 km) |
| League City to Urbana (Illinois) | 831.49 mi (1,338.16 km) |
| League City to Urbana (Maryland) | 1,216.23 mi (1,957.33 km) |
| League City to Urbana (Ohio) | 974.78 mi (1,568.76 km) |
| League City to Urbandale (Iowa) | 842.87 mi (1,356.47 km) |
| League City to Utica (New York) | 1,445.91 mi (2,326.97 km) |
| League City to Uvalde (Texas) | 281.82 mi (453.55 km) |
| League City to Vacaville (California) | 1,649.85 mi (2,655.19 km) |
| League City to Vadnais Heights (Minnesota) | 1,081.45 mi (1,740.43 km) |
| League City to Vail (Arizona) | 940.91 mi (1,514.25 km) |
| League City to Valdosta (Georgia) | 712.55 mi (1,146.74 km) |
