| League City to Superior (Colorado) | 918.88 mi (1,478.79 km) |
| League City to Superior (Wisconsin) | 1,199.96 mi (1,931.15 km) |
| League City to Surprise (Arizona) | 1,059.60 mi (1,705.27 km) |
| League City to Susanville (California) | 1,621.60 mi (2,609.71 km) |
| League City to Sussex (Wisconsin) | 1,016.97 mi (1,636.65 km) |
| League City to Suwanee (Georgia) | 720.52 mi (1,159.56 km) |
| League City to Swansea (Illinois) | 691.21 mi (1,112.39 km) |
| League City to Sweetwater (Florida) | 936.73 mi (1,507.52 km) |
| League City to Sweetwater (Texas) | 375.46 mi (604.25 km) |
| League City to Sycamore (Illinois) | 935.65 mi (1,505.78 km) |
| League City to Sylacauga (Alabama) | 580.83 mi (934.75 km) |
| League City to Sylvania (Ohio) | 1,057.79 mi (1,702.35 km) |
| League City to Syosset (New York) | 1,443.79 mi (2,323.56 km) |
| League City to Syracuse (New York) | 1,405.68 mi (2,262.23 km) |
| League City to Syracuse (Utah) | 1,243.86 mi (2,001.80 km) |
