| League City to Storm Lake (Iowa) | 908.98 mi (1,462.87 km) |
| League City to Storrs (Connecticut) | 1,532.32 mi (2,466.03 km) |
| League City to Stoughton (Wisconsin) | 983.98 mi (1,583.56 km) |
| League City to Stow (Ohio) | 1,113.67 mi (1,792.28 km) |
| League City to Streamwood (Illinois) | 948.34 mi (1,526.20 km) |
| League City to Streator (Illinois) | 877.90 mi (1,412.85 km) |
| League City to Streetsboro (Ohio) | 1,120.02 mi (1,802.49 km) |
| League City to Strongsville (Ohio) | 1,104.95 mi (1,778.24 km) |
| League City to Stuart (Florida) | 917.00 mi (1,475.77 km) |
| League City to Stuarts Draft (Virginia) | 1,092.99 mi (1,759.00 km) |
| League City to Sturgis (Michigan) | 1,008.23 mi (1,622.58 km) |
| League City to Suamico (Wisconsin) | 1,115.19 mi (1,794.72 km) |
| League City to Sudley (Virginia) | 1,191.47 mi (1,917.48 km) |
| League City to Suffern (New York) | 1,423.30 mi (2,290.59 km) |
| League City to Suffolk (Virginia) | 1,176.69 mi (1,893.69 km) |
