| League City to St. Simons (Georgia) | 826.11 mi (1,329.49 km) |
| League City to Stafford (Texas) | 29.10 mi (46.83 km) |
| League City to Stallings (North Carolina) | 927.69 mi (1,492.98 km) |
| League City to Stamford (Connecticut) | 1,450.01 mi (2,333.56 km) |
| League City to Stanford (California) | 1,646.46 mi (2,649.71 km) |
| League City to Stanton (California) | 1,375.60 mi (2,213.81 km) |
| League City to Star (Idaho) | 1,531.85 mi (2,465.27 km) |
| League City to Starkville (Mississippi) | 460.57 mi (741.21 km) |
| League City to State College (Pennsylvania) | 1,245.01 mi (2,003.65 km) |
| League City to Staten Island (New York) | 1,406.27 mi (2,263.18 km) |
| League City to Statesboro (Georgia) | 815.22 mi (1,311.98 km) |
| League City to Statesville (North Carolina) | 934.32 mi (1,503.64 km) |
| League City to Staunton (Virginia) | 1,096.33 mi (1,764.38 km) |
| League City to Steamboat Springs (Colorado) | 1,006.30 mi (1,619.48 km) |
| League City to Steiner Ranch (Texas) | 177.58 mi (285.79 km) |
