| League City to Smyrna (Delaware) | 1,297.74 mi (2,088.51 km) |
| League City to Smyrna (Georgia) | 691.81 mi (1,113.36 km) |
| League City to Smyrna (Tennessee) | 669.81 mi (1,077.96 km) |
| League City to Snellville (Georgia) | 718.83 mi (1,156.85 km) |
| League City to Snoqualmie (Washington) | 1,891.49 mi (3,044.05 km) |
| League City to Snyder (Texas) | 409.21 mi (658.55 km) |
| League City to Socastee (South Carolina) | 989.77 mi (1,592.89 km) |
| League City to Socorro (Texas) | 679.54 mi (1,093.62 km) |
| League City to Soddy-Daisy (Tennessee) | 702.96 mi (1,131.31 km) |
| League City to Solana Beach (California) | 1,328.07 mi (2,137.32 km) |
| League City to Soledad (California) | 1,589.06 mi (2,557.35 km) |
| League City to Solon (Ohio) | 1,123.25 mi (1,807.69 km) |
| League City to Somers Point (New Jersey) | 1,347.04 mi (2,167.86 km) |
| League City to Somerset (Kentucky) | 800.97 mi (1,289.03 km) |
| League City to Somerset (New Jersey) | 1,387.45 mi (2,232.89 km) |
