| Le Mars to Enterprise (Nevada) | 1,116.48 mi (1,796.80 km) |
| Le Mars to Enumclaw (Washington) | 1,291.49 mi (2,078.45 km) |
| Le Mars to Ephrata (Pennsylvania) | 1,047.75 mi (1,686.19 km) |
| Le Mars to Erie (Colorado) | 496.63 mi (799.25 km) |
| Le Mars to Erie (Pennsylvania) | 820.85 mi (1,321.03 km) |
| Le Mars to Erlanger (Kentucky) | 658.11 mi (1,059.12 km) |
| Le Mars to Escanaba (Michigan) | 493.59 mi (794.36 km) |
| Le Mars to Escondido (California) | 1,313.89 mi (2,114.50 km) |
| Le Mars to Española (New Mexico) | 705.08 mi (1,134.72 km) |
| Le Mars to Essex (Maryland) | 1,053.17 mi (1,694.92 km) |
| Le Mars to Essex Junction (Vermont) | 1,155.25 mi (1,859.20 km) |
| Le Mars to Estelle (Louisiana) | 954.90 mi (1,536.77 km) |
| Le Mars to Estero (Florida) | 1,390.36 mi (2,237.57 km) |
| Le Mars to Euclid (Ohio) | 753.79 mi (1,213.10 km) |
| Le Mars to Eufaula (Alabama) | 962.96 mi (1,549.74 km) |
