| Laredo to Enumclaw (Washington) | 5,143.54 mi (8,277.73 km) |
| Laredo to Ephrata (Pennsylvania) | 3,632.15 mi (5,845.38 km) |
| Laredo to Erie (Colorado) | 4,886.93 mi (7,864.75 km) |
| Laredo to Erie (Pennsylvania) | 3,743.64 mi (6,024.81 km) |
| Laredo to Erlanger (Kentucky) | 4,057.28 mi (6,529.56 km) |
| Laredo to Escanaba (Michigan) | 3,922.08 mi (6,311.99 km) |
| Laredo to Escondido (California) | 5,696.15 mi (9,167.07 km) |
| Laredo to Española (New Mexico) | 5,114.57 mi (8,231.10 km) |
| Laredo to Essex (Maryland) | 3,674.21 mi (5,913.06 km) |
| Laredo to Essex Junction (Vermont) | 3,357.60 mi (5,403.54 km) |
| Laredo to Estelle (Louisiana) | 4,682.24 mi (7,535.33 km) |
| Laredo to Estero (Florida) | 4,428.69 mi (7,127.28 km) |
| Laredo to Euclid (Ohio) | 3,826.27 mi (6,157.79 km) |
| Laredo to Eufaula (Alabama) | 4,362.31 mi (7,020.46 km) |
| Laredo to Eugene (Oregon) | 5,343.53 mi (8,599.59 km) |
