| Laramie to Southern Pines (North Carolina) | 1,476.86 mi (2,376.77 km) |
| Laramie to Southfield (Michigan) | 1,148.90 mi (1,848.98 km) |
| Laramie to Southgate (Michigan) | 1,153.01 mi (1,855.59 km) |
| Laramie to Southlake (Texas) | 741.05 mi (1,192.61 km) |
| Laramie to Spanaway (Washington) | 921.34 mi (1,482.75 km) |
| Laramie to Spanish Fork (Utah) | 326.54 mi (525.51 km) |
| Laramie to Spanish Lake (Missouri) | 831.78 mi (1,338.62 km) |
| Laramie to Spanish Springs (Nevada) | 746.85 mi (1,201.94 km) |
| Laramie to Sparks (Nevada) | 750.61 mi (1,207.99 km) |
| Laramie to Spartanburg (South Carolina) | 1,355.17 mi (2,180.94 km) |
| Laramie to Spearfish (South Dakota) | 237.77 mi (382.65 km) |
| Laramie to Speedway (Indiana) | 1,019.63 mi (1,640.94 km) |
| Laramie to Spencer (Iowa) | 549.35 mi (884.09 km) |
| Laramie to Spokane (Washington) | 728.48 mi (1,172.37 km) |
| Laramie to Spokane Valley (Washington) | 720.56 mi (1,159.64 km) |
