| Lakeland South to Southern Pines (North Carolina) | 2,344.56 mi (3,773.20 km) |
| Lakeland South to Southfield (Michigan) | 1,918.46 mi (3,087.46 km) |
| Lakeland South to Southgate (Michigan) | 1,928.58 mi (3,103.76 km) |
| Lakeland South to Southlake (Texas) | 1,643.85 mi (2,645.52 km) |
| Lakeland South to Spanaway (Washington) | 14.13 mi (22.73 km) |
| Lakeland South to Spanish Fork (Utah) | 725.39 mi (1,167.41 km) |
| Lakeland South to Spanish Lake (Missouri) | 1,708.39 mi (2,749.38 km) |
| Lakeland South to Spanish Springs (Nevada) | 542.59 mi (873.21 km) |
| Lakeland South to Sparks (Nevada) | 547.63 mi (881.33 km) |
| Lakeland South to Spartanburg (South Carolina) | 2,236.82 mi (3,599.82 km) |
| Lakeland South to Spearfish (South Dakota) | 906.54 mi (1,458.93 km) |
| Lakeland South to Speedway (Indiana) | 1,859.12 mi (2,991.96 km) |
| Lakeland South to Spencer (Iowa) | 1,343.74 mi (2,162.55 km) |
| Lakeland South to Spokane (Washington) | 228.04 mi (366.99 km) |
| Lakeland South to Spokane Valley (Washington) | 237.21 mi (381.75 km) |
