| Laguna Woods to Superior (Colorado) | 820.36 mi (1,320.24 km) |
| Laguna Woods to Superior (Wisconsin) | 1,616.76 mi (2,601.92 km) |
| Laguna Woods to Surprise (Arizona) | 303.61 mi (488.62 km) |
| Laguna Woods to Susanville (California) | 496.65 mi (799.28 km) |
| Laguna Woods to Sussex (Wisconsin) | 1,717.22 mi (2,763.60 km) |
| Laguna Woods to Suwanee (Georgia) | 1,923.41 mi (3,095.44 km) |
| Laguna Woods to Swansea (Illinois) | 1,579.99 mi (2,542.75 km) |
| Laguna Woods to Sweetwater (Florida) | 2,293.19 mi (3,690.53 km) |
| Laguna Woods to Sweetwater (Texas) | 1,005.14 mi (1,617.61 km) |
| Laguna Woods to Sycamore (Illinois) | 1,678.48 mi (2,701.26 km) |
| Laguna Woods to Sylacauga (Alabama) | 1,808.54 mi (2,910.57 km) |
| Laguna Woods to Sylvania (Ohio) | 1,929.05 mi (3,104.50 km) |
| Laguna Woods to Syosset (New York) | 2,457.29 mi (3,954.63 km) |
| Laguna Woods to Syracuse (New York) | 2,320.47 mi (3,734.44 km) |
| Laguna Woods to Syracuse (Utah) | 602.55 mi (969.71 km) |
