| Laguna Woods to Stephenville (Texas) | 1,134.04 mi (1,825.06 km) |
| Laguna Woods to Sterling (Colorado) | 934.20 mi (1,503.45 km) |
| Laguna Woods to Sterling (Illinois) | 1,624.74 mi (2,614.76 km) |
| Laguna Woods to Sterling (Virginia) | 2,257.29 mi (3,632.76 km) |
| Laguna Woods to Sterling Heights (Michigan) | 1,970.09 mi (3,170.56 km) |
| Laguna Woods to Steubenville (Ohio) | 2,082.80 mi (3,351.94 km) |
| Laguna Woods to Stevens Point (Wisconsin) | 1,677.70 mi (2,699.99 km) |
| Laguna Woods to Stevenson Ranch (California) | 72.93 mi (117.36 km) |
| Laguna Woods to Stillwater (Minnesota) | 1,538.52 mi (2,476.00 km) |
| Laguna Woods to Stillwater (Oklahoma) | 1,181.51 mi (1,901.45 km) |
| Laguna Woods to Stockbridge (Georgia) | 1,920.06 mi (3,090.05 km) |
| Laguna Woods to Stockton (California) | 362.28 mi (583.04 km) |
| Laguna Woods to Stone Ridge (Virginia) | 2,249.51 mi (3,620.23 km) |
| Laguna Woods to Stonecrest (Georgia) | 1,923.50 mi (3,095.57 km) |
| Laguna Woods to Stony Brook (New York) | 2,476.51 mi (3,985.55 km) |
