| Laguna Woods to St. George (Utah) | 334.85 mi (538.89 km) |
| Laguna Woods to St. Helens (Oregon) | 887.83 mi (1,428.82 km) |
| Laguna Woods to St. James (New York) | 2,475.34 mi (3,983.68 km) |
| Laguna Woods to St. John (Indiana) | 1,733.89 mi (2,790.43 km) |
| Laguna Woods to St. Joseph (Missouri) | 1,334.14 mi (2,147.09 km) |
| Laguna Woods to St. Louis (Missouri) | 1,566.45 mi (2,520.95 km) |
| Laguna Woods to St. Louis Park (Minnesota) | 1,511.56 mi (2,432.63 km) |
| Laguna Woods to St. Marys (Georgia) | 2,112.90 mi (3,400.38 km) |
| Laguna Woods to St. Marys (Pennsylvania) | 2,194.90 mi (3,532.35 km) |
| Laguna Woods to St. Matthews (Kentucky) | 1,814.47 mi (2,920.10 km) |
| Laguna Woods to St. Michael (Minnesota) | 1,503.80 mi (2,420.14 km) |
| Laguna Woods to St. Paul (Minnesota) | 1,523.32 mi (2,451.55 km) |
| Laguna Woods to St. Peter (Minnesota) | 1,467.91 mi (2,362.38 km) |
| Laguna Woods to St. Peters (Missouri) | 1,547.86 mi (2,491.04 km) |
| Laguna Woods to St. Petersburg (Florida) | 2,111.20 mi (3,397.66 km) |
