| Laguna Woods to Seymour (Tennessee) | 1,924.93 mi (3,097.88 km) |
| Laguna Woods to Shady Hills (Florida) | 2,104.09 mi (3,386.20 km) |
| Laguna Woods to Shafter (California) | 153.93 mi (247.73 km) |
| Laguna Woods to Shaker Heights (Ohio) | 2,038.98 mi (3,281.42 km) |
| Laguna Woods to Shakopee (Minnesota) | 1,501.85 mi (2,417.00 km) |
| Laguna Woods to Sharon (Pennsylvania) | 2,092.50 mi (3,367.55 km) |
| Laguna Woods to Sharonville (Ohio) | 1,881.92 mi (3,028.66 km) |
| Laguna Woods to Shasta Lake (California) | 551.22 mi (887.10 km) |
| Laguna Woods to Shawnee (Kansas) | 1,325.65 mi (2,133.43 km) |
| Laguna Woods to Shawnee (Oklahoma) | 1,186.59 mi (1,909.64 km) |
| Laguna Woods to Sheboygan (Wisconsin) | 1,750.62 mi (2,817.35 km) |
| Laguna Woods to Shelby (North Carolina) | 2,053.51 mi (3,304.80 km) |
| Laguna Woods to Shelbyville (Indiana) | 1,809.41 mi (2,911.96 km) |
| Laguna Woods to Shelbyville (Kentucky) | 1,836.67 mi (2,955.84 km) |
| Laguna Woods to Shelbyville (Tennessee) | 1,777.22 mi (2,860.17 km) |
