| Laguna Woods to Sanford (Maine) | 2,591.81 mi (4,171.12 km) |
| Laguna Woods to Sanford (North Carolina) | 2,183.89 mi (3,514.63 km) |
| Laguna Woods to Sanger (California) | 237.08 mi (381.54 km) |
| Laguna Woods to Santa Ana (California) | 12.38 mi (19.92 km) |
| Laguna Woods to Santa Barbara (California) | 127.24 mi (204.77 km) |
| Laguna Woods to Santa Clara (California) | 352.26 mi (566.91 km) |
| Laguna Woods to Santa Clara (Oregon) | 781.47 mi (1,257.65 km) |
| Laguna Woods to Santa Clarita (California) | 71.00 mi (114.26 km) |
| Laguna Woods to Santa Cruz (California) | 336.25 mi (541.14 km) |
| Laguna Woods to Santa Fe (New Mexico) | 682.29 mi (1,098.03 km) |
| Laguna Woods to Santa Fe (Texas) | 1,361.72 mi (2,191.48 km) |
| Laguna Woods to Santa Fe Springs (California) | 29.38 mi (47.28 km) |
| Laguna Woods to Santa Maria (California) | 179.88 mi (289.48 km) |
| Laguna Woods to Santa Monica (California) | 51.73 mi (83.25 km) |
| Laguna Woods to Santa Paula (California) | 92.21 mi (148.40 km) |
