| Laguna Woods to Olympia Heights (Florida) | 2,296.78 mi (3,696.31 km) |
| Laguna Woods to Omaha (Nebraska) | 1,296.84 mi (2,087.07 km) |
| Laguna Woods to On Top of the World Designated Place (Florida) | 2,103.91 mi (3,385.92 km) |
| Laguna Woods to Onalaska (Wisconsin) | 1,586.29 mi (2,552.89 km) |
| Laguna Woods to Oneida (New York) | 2,344.85 mi (3,773.68 km) |
| Laguna Woods to Oneonta (New York) | 2,374.18 mi (3,820.87 km) |
| Laguna Woods to Ontario (California) | 30.50 mi (49.09 km) |
| Laguna Woods to Ontario (Oregon) | 720.81 mi (1,160.03 km) |
| Laguna Woods to Opa-locka (Florida) | 2,296.93 mi (3,696.55 km) |
| Laguna Woods to Opelika (Alabama) | 1,865.37 mi (3,002.02 km) |
| Laguna Woods to Opelousas (Louisiana) | 1,512.85 mi (2,434.69 km) |
| Laguna Woods to Orange (California) | 14.40 mi (23.18 km) |
| Laguna Woods to Orange (Texas) | 1,423.68 mi (2,291.19 km) |
| Laguna Woods to Orange City (Florida) | 2,164.96 mi (3,484.17 km) |
| Laguna Woods to Orangeburg (South Carolina) | 2,111.14 mi (3,397.56 km) |
