| La Spezia to Southern Pines (North Carolina) | 4,550.10 mi (7,322.67 km) |
| La Spezia to Southfield (Michigan) | 4,408.14 mi (7,094.22 km) |
| La Spezia to Southgate (Michigan) | 4,417.20 mi (7,108.80 km) |
| La Spezia to Southlake (Texas) | 5,410.31 mi (8,707.05 km) |
| La Spezia to Spanaway (Washington) | 5,497.34 mi (8,847.12 km) |
| La Spezia to Spanish Fork (Utah) | 5,575.34 mi (8,972.64 km) |
| La Spezia to Spanish Lake (Missouri) | 4,851.28 mi (7,807.38 km) |
| La Spezia to Spanish Springs (Nevada) | 5,851.46 mi (9,417.02 km) |
| La Spezia to Sparks (Nevada) | 5,857.62 mi (9,426.93 km) |
| La Spezia to Spartanburg (South Carolina) | 4,672.24 mi (7,519.25 km) |
| La Spezia to Spearfish (South Dakota) | 5,085.29 mi (8,183.98 km) |
| La Spezia to Speedway (Indiana) | 4,644.83 mi (7,475.14 km) |
| La Spezia to Spencer (Iowa) | 4,842.64 mi (7,793.47 km) |
| La Spezia to Spokane (Washington) | 5,333.29 mi (8,583.10 km) |
| La Spezia to Spokane Valley (Washington) | 5,328.12 mi (8,574.79 km) |
