| La Puebla del Rio to Southern Pines (North Carolina) | 3,982.32 mi (6,408.92 km) |
| La Puebla del Rio to Southfield (Michigan) | 3,965.63 mi (6,382.06 km) |
| La Puebla del Rio to Southgate (Michigan) | 3,970.38 mi (6,389.70 km) |
| La Puebla del Rio to Southlake (Texas) | 4,943.25 mi (7,955.40 km) |
| La Puebla del Rio to Spanaway (Washington) | 5,409.55 mi (8,705.82 km) |
| La Puebla del Rio to Spanish Fork (Utah) | 5,313.75 mi (8,551.66 km) |
| La Puebla del Rio to Spanish Lake (Missouri) | 4,403.89 mi (7,087.37 km) |
| La Puebla del Rio to Spanish Springs (Nevada) | 5,658.51 mi (9,106.49 km) |
| La Puebla del Rio to Sparks (Nevada) | 5,664.23 mi (9,115.70 km) |
| La Puebla del Rio to Spartanburg (South Carolina) | 4,117.98 mi (6,627.26 km) |
| La Puebla del Rio to Spearfish (South Dakota) | 4,812.82 mi (7,745.49 km) |
| La Puebla del Rio to Speedway (Indiana) | 4,183.66 mi (6,732.95 km) |
| La Puebla del Rio to Spencer (Iowa) | 4,488.58 mi (7,223.67 km) |
| La Puebla del Rio to Spokane (Washington) | 5,208.98 mi (8,383.05 km) |
| La Puebla del Rio to Spokane Valley (Washington) | 5,202.11 mi (8,371.98 km) |
