| La Grande to University Place (Washington) | 249.80 mi (402.02 km) |
| La Grande to Upland (California) | 774.62 mi (1,246.62 km) |
| La Grande to Upper Arlington (Ohio) | 1,801.09 mi (2,898.58 km) |
| La Grande to Upper Grand Lagoon (Florida) | 2,033.85 mi (3,273.17 km) |
| La Grande to Upper Montclair (New Jersey) | 2,208.37 mi (3,554.03 km) |
| La Grande to Urbana (Illinois) | 1,549.83 mi (2,494.20 km) |
| La Grande to Urbana (Maryland) | 2,098.90 mi (3,377.85 km) |
| La Grande to Urbana (Ohio) | 1,765.66 mi (2,841.56 km) |
| La Grande to Urbandale (Iowa) | 1,239.80 mi (1,995.27 km) |
| La Grande to Utica (New York) | 2,103.11 mi (3,384.63 km) |
| La Grande to Uvalde (Texas) | 1,493.54 mi (2,403.61 km) |
| La Grande to Vacaville (California) | 520.91 mi (838.33 km) |
| La Grande to Vadnais Heights (Minnesota) | 1,213.14 mi (1,952.35 km) |
| La Grande to Vail (Arizona) | 1,000.81 mi (1,610.65 km) |
| La Grande to Valdosta (Georgia) | 2,118.02 mi (3,408.62 km) |
