| La Grande to Seymour (Tennessee) | 1,897.92 mi (3,054.41 km) |
| La Grande to Shady Hills (Florida) | 2,259.41 mi (3,636.17 km) |
| La Grande to Shafter (California) | 682.71 mi (1,098.72 km) |
| La Grande to Shaker Heights (Ohio) | 1,837.35 mi (2,956.93 km) |
| La Grande to Shakopee (Minnesota) | 1,197.21 mi (1,926.72 km) |
| La Grande to Sharon (Pennsylvania) | 1,894.13 mi (3,048.31 km) |
| La Grande to Sharonville (Ohio) | 1,757.14 mi (2,827.84 km) |
| La Grande to Shasta Lake (California) | 387.20 mi (623.13 km) |
| La Grande to Shawnee (Kansas) | 1,263.81 mi (2,033.91 km) |
| La Grande to Shawnee (Oklahoma) | 1,302.39 mi (2,095.99 km) |
| La Grande to Sheboygan (Wisconsin) | 1,490.22 mi (2,398.27 km) |
| La Grande to Shelby (North Carolina) | 2,025.85 mi (3,260.29 km) |
| La Grande to Shelbyville (Indiana) | 1,683.26 mi (2,708.94 km) |
| La Grande to Shelbyville (Kentucky) | 1,749.65 mi (2,815.79 km) |
| La Grande to Shelbyville (Tennessee) | 1,782.99 mi (2,869.44 km) |
