| La Grande to Security-Widefield (Colorado) | 821.32 mi (1,321.78 km) |
| La Grande to Sedalia (Missouri) | 1,348.70 mi (2,170.52 km) |
| La Grande to Sedro-Woolley (Washington) | 294.47 mi (473.91 km) |
| La Grande to Seguin (Texas) | 1,540.69 mi (2,479.50 km) |
| La Grande to Selden (New York) | 2,263.10 mi (3,642.11 km) |
| La Grande to Selma (Alabama) | 1,877.11 mi (3,020.92 km) |
| La Grande to Selma (California) | 609.95 mi (981.62 km) |
| La Grande to Selma (Texas) | 1,527.64 mi (2,458.50 km) |
| La Grande to Seminole (Florida) | 2,274.07 mi (3,659.76 km) |
| La Grande to Seven Hills (Ohio) | 1,833.66 mi (2,950.99 km) |
| La Grande to Seven Oaks (South Carolina) | 2,090.86 mi (3,364.92 km) |
| La Grande to Severn (Maryland) | 2,135.87 mi (3,437.34 km) |
| La Grande to Severna Park (Maryland) | 2,143.45 mi (3,449.55 km) |
| La Grande to Sevierville (Tennessee) | 1,907.19 mi (3,069.32 km) |
| La Grande to Seymour (Indiana) | 1,694.96 mi (2,727.77 km) |
