| La Grande to Scottsboro (Alabama) | 1,834.10 mi (2,951.70 km) |
| La Grande to Scottsdale (Arizona) | 869.07 mi (1,398.63 km) |
| La Grande to Scranton (Pennsylvania) | 2,123.14 mi (3,416.86 km) |
| La Grande to Seabrook (Maryland) | 2,132.95 mi (3,432.66 km) |
| La Grande to Seabrook (Texas) | 1,657.84 mi (2,668.04 km) |
| La Grande to Seaford (New York) | 2,247.23 mi (3,616.57 km) |
| La Grande to Seagoville (Texas) | 1,443.00 mi (2,322.29 km) |
| La Grande to Seal Beach (California) | 799.41 mi (1,286.53 km) |
| La Grande to Searcy (Arkansas) | 1,544.14 mi (2,485.05 km) |
| La Grande to Seaside (California) | 631.80 mi (1,016.78 km) |
| La Grande to SeaTac (Washington) | 248.46 mi (399.86 km) |
| La Grande to Seattle (Washington) | 256.55 mi (412.88 km) |
| La Grande to Sebastian (Florida) | 2,382.78 mi (3,834.71 km) |
| La Grande to Sebring (Florida) | 2,351.84 mi (3,784.92 km) |
| La Grande to Secaucus (New Jersey) | 2,216.54 mi (3,567.18 km) |
