| La Grande to Santa Rosa (California) | 531.13 mi (854.77 km) |
| La Grande to Santaquin (Utah) | 488.64 mi (786.38 km) |
| La Grande to Santee (California) | 863.51 mi (1,389.68 km) |
| La Grande to Sapulpa (Oklahoma) | 1,313.60 mi (2,114.04 km) |
| La Grande to Saraland (Alabama) | 1,896.27 mi (3,051.75 km) |
| La Grande to Sarasota (Florida) | 2,308.32 mi (3,714.88 km) |
| La Grande to Sarasota Springs (Florida) | 2,312.84 mi (3,722.15 km) |
| La Grande to Saratoga (California) | 592.79 mi (954.00 km) |
| La Grande to Saratoga Springs (New York) | 2,172.69 mi (3,496.61 km) |
| La Grande to Saratoga Springs (Utah) | 464.60 mi (747.71 km) |
| La Grande to Sartell (Minnesota) | 1,152.26 mi (1,854.38 km) |
| La Grande to Satellite Beach (Florida) | 2,359.43 mi (3,797.14 km) |
| La Grande to Sauk Rapids (Minnesota) | 1,155.65 mi (1,859.84 km) |
| La Grande to Sault Ste. Marie (Michigan) | 1,610.62 mi (2,592.05 km) |
| La Grande to Savage (Minnesota) | 1,202.96 mi (1,935.97 km) |
