| La Grande to Sanford (Maine) | 2,307.25 mi (3,713.16 km) |
| La Grande to Sanford (North Carolina) | 2,133.28 mi (3,433.18 km) |
| La Grande to Sanger (California) | 600.83 mi (966.94 km) |
| La Grande to Santa Ana (California) | 800.69 mi (1,288.59 km) |
| La Grande to Santa Barbara (California) | 757.74 mi (1,219.47 km) |
| La Grande to Santa Clara (California) | 585.46 mi (942.21 km) |
| La Grande to Santa Clara (Oregon) | 261.47 mi (420.79 km) |
| La Grande to Santa Clarita (California) | 753.89 mi (1,213.27 km) |
| La Grande to Santa Cruz (California) | 611.89 mi (984.74 km) |
| La Grande to Santa Fe (New Mexico) | 920.07 mi (1,480.71 km) |
| La Grande to Santa Fe (Texas) | 1,664.22 mi (2,678.30 km) |
| La Grande to Santa Fe Springs (California) | 787.06 mi (1,266.66 km) |
| La Grande to Santa Maria (California) | 728.56 mi (1,172.51 km) |
| La Grande to Santa Monica (California) | 781.08 mi (1,257.03 km) |
| La Grande to Santa Paula (California) | 759.69 mi (1,222.61 km) |
