| La Crosse to Stephenville (Texas) | 887.05 mi (1,427.57 km) |
| La Crosse to Sterling (Colorado) | 650.29 mi (1,046.55 km) |
| La Crosse to Sterling (Illinois) | 159.96 mi (257.43 km) |
| La Crosse to Sterling (Virginia) | 788.47 mi (1,268.92 km) |
| La Crosse to Sterling Heights (Michigan) | 421.46 mi (678.27 km) |
| La Crosse to Steubenville (Ohio) | 591.93 mi (952.62 km) |
| La Crosse to Stevens Point (Wisconsin) | 96.11 mi (154.68 km) |
| La Crosse to Stevenson Ranch (California) | 1,595.61 mi (2,567.88 km) |
| La Crosse to Stillwater (Minnesota) | 116.29 mi (187.15 km) |
| La Crosse to Stillwater (Oklahoma) | 614.70 mi (989.26 km) |
| La Crosse to Stockbridge (Georgia) | 804.74 mi (1,295.10 km) |
| La Crosse to Stockton (California) | 1,612.48 mi (2,595.03 km) |
| La Crosse to Stone Ridge (Virginia) | 784.03 mi (1,261.77 km) |
| La Crosse to Stonecrest (Georgia) | 797.23 mi (1,283.01 km) |
| La Crosse to Stony Brook (New York) | 943.65 mi (1,518.66 km) |
