| La Crosse to St. Simons (Georgia) | 1,025.17 mi (1,649.85 km) |
| La Crosse to Stafford (Texas) | 1,009.52 mi (1,624.66 km) |
| La Crosse to Stallings (North Carolina) | 823.45 mi (1,325.22 km) |
| La Crosse to Stamford (Connecticut) | 918.07 mi (1,477.49 km) |
| La Crosse to Stanford (California) | 1,670.91 mi (2,689.06 km) |
| La Crosse to Stanton (California) | 1,589.25 mi (2,557.65 km) |
| La Crosse to Star (Idaho) | 1,255.78 mi (2,020.99 km) |
| La Crosse to Starkville (Mississippi) | 727.53 mi (1,170.85 km) |
| La Crosse to State College (Pennsylvania) | 713.66 mi (1,148.53 km) |
| La Crosse to Staten Island (New York) | 900.45 mi (1,449.14 km) |
| La Crosse to Statesboro (Georgia) | 938.15 mi (1,509.81 km) |
| La Crosse to Statesville (North Carolina) | 780.29 mi (1,255.76 km) |
| La Crosse to Staunton (Virginia) | 744.32 mi (1,197.87 km) |
| La Crosse to Steamboat Springs (Colorado) | 830.31 mi (1,336.25 km) |
| La Crosse to Steiner Ranch (Texas) | 999.03 mi (1,607.79 km) |
