| La Crosse to Shoreview (Minnesota) | 128.23 mi (206.37 km) |
| La Crosse to Shorewood (Illinois) | 220.94 mi (355.57 km) |
| La Crosse to Shorewood (Wisconsin) | 175.00 mi (281.64 km) |
| La Crosse to Short Hills (New Jersey) | 888.03 mi (1,429.15 km) |
| La Crosse to Short Pump (Virginia) | 828.55 mi (1,333.42 km) |
| La Crosse to Show Low (Arizona) | 1,201.80 mi (1,934.11 km) |
| La Crosse to Shreveport (Louisiana) | 797.02 mi (1,282.68 km) |
| La Crosse to Sicklerville (New Jersey) | 880.80 mi (1,417.51 km) |
| La Crosse to Sidney (Ohio) | 436.60 mi (702.64 km) |
| La Crosse to Sierra Madre (California) | 1,577.97 mi (2,539.50 km) |
| La Crosse to Sierra Vista (Arizona) | 1,338.43 mi (2,154.00 km) |
| La Crosse to Sierra Vista Southeast (Arizona) | 1,339.67 mi (2,155.99 km) |
| La Crosse to Signal Hill (California) | 1,597.48 mi (2,570.90 km) |
| La Crosse to Sikeston (Missouri) | 487.09 mi (783.90 km) |
| La Crosse to Siloam Springs (Arkansas) | 555.94 mi (894.71 km) |
