| La Crosse to Shelton (Connecticut) | 934.80 mi (1,504.41 km) |
| La Crosse to Shelton (Washington) | 1,550.20 mi (2,494.80 km) |
| La Crosse to Shenandoah (Louisiana) | 927.47 mi (1,492.61 km) |
| La Crosse to Shepherdsville (Kentucky) | 495.98 mi (798.20 km) |
| La Crosse to Sheridan (Wyoming) | 779.74 mi (1,254.87 km) |
| La Crosse to Sherman (Texas) | 761.75 mi (1,225.92 km) |
| La Crosse to Sherrelwood (Colorado) | 759.56 mi (1,222.39 km) |
| La Crosse to Sherwood (Arkansas) | 622.18 mi (1,001.30 km) |
| La Crosse to Sherwood (Oregon) | 1,549.20 mi (2,493.19 km) |
| La Crosse to Shiloh (Illinois) | 370.48 mi (596.23 km) |
| La Crosse to Shiloh (Ohio) | 454.07 mi (730.75 km) |
| La Crosse to Shiloh (Pennsylvania) | 787.32 mi (1,267.07 km) |
| La Crosse to Shirley (New York) | 958.66 mi (1,542.81 km) |
| La Crosse to Shively (Kentucky) | 480.19 mi (772.79 km) |
| La Crosse to Shoreline (Washington) | 1,512.87 mi (2,434.74 km) |
