| La Crosse to Saddlebrooke (Arizona) | 1,315.11 mi (2,116.46 km) |
| La Crosse to Safety Harbor (Florida) | 1,190.86 mi (1,916.50 km) |
| La Crosse to Saginaw (Michigan) | 364.91 mi (587.27 km) |
| La Crosse to Saginaw (Texas) | 826.39 mi (1,329.94 km) |
| La Crosse to Sahuarita (Arizona) | 1,348.26 mi (2,169.81 km) |
| La Crosse to Saks (Alabama) | 755.84 mi (1,216.41 km) |
| La Crosse to Salem (Massachusetts) | 1,025.62 mi (1,650.57 km) |
| La Crosse to Salem (Ohio) | 566.39 mi (911.52 km) |
| La Crosse to Salem (Oregon) | 1,562.16 mi (2,514.06 km) |
| La Crosse to Salem (Virginia) | 739.12 mi (1,189.51 km) |
| La Crosse to Salem Lakes (Wisconsin) | 179.56 mi (288.97 km) |
| La Crosse to Salida (California) | 1,608.86 mi (2,589.21 km) |
| La Crosse to Salina (Kansas) | 478.99 mi (770.86 km) |
| La Crosse to Salinas (California) | 1,666.57 mi (2,682.08 km) |
| La Crosse to Salisbury (Maryland) | 895.23 mi (1,440.73 km) |
