| La Crosse to Odessa (Texas) | 1,022.13 mi (1,644.96 km) |
| La Crosse to Ogden (Utah) | 1,068.34 mi (1,719.33 km) |
| La Crosse to Oildale (California) | 1,579.90 mi (2,542.60 km) |
| La Crosse to Ojus (Florida) | 1,381.72 mi (2,223.66 km) |
| La Crosse to Okemos (Michigan) | 351.29 mi (565.34 km) |
| La Crosse to Oklahoma City (Oklahoma) | 666.77 mi (1,073.06 km) |
| La Crosse to Okmulgee (Oklahoma) | 621.30 mi (999.89 km) |
| La Crosse to Olathe (Kansas) | 388.83 mi (625.77 km) |
| La Crosse to Old Jamestown (Missouri) | 347.85 mi (559.82 km) |
| La Crosse to Oldsmar (Florida) | 1,188.70 mi (1,913.03 km) |
| La Crosse to Olean (New York) | 657.43 mi (1,058.03 km) |
| La Crosse to Olive Branch (Mississippi) | 616.77 mi (992.60 km) |
| La Crosse to Olivehurst (California) | 1,595.06 mi (2,567.00 km) |
| La Crosse to Olney (Maryland) | 799.41 mi (1,286.53 km) |
| La Crosse to Olympia (Washington) | 1,540.74 mi (2,479.59 km) |
