| La Crosse to Indianapolis (Indiana) | 382.83 mi (616.11 km) |
| La Crosse to Indianola (Iowa) | 207.50 mi (333.94 km) |
| La Crosse to Indio (California) | 1,508.36 mi (2,427.46 km) |
| La Crosse to Inglewood (California) | 1,600.07 mi (2,575.07 km) |
| La Crosse to Inkster (Michigan) | 413.00 mi (664.66 km) |
| La Crosse to Inver Grove Heights (Minnesota) | 113.95 mi (183.39 km) |
| La Crosse to Inwood (New York) | 919.23 mi (1,479.36 km) |
| La Crosse to Iona (Florida) | 1,303.32 mi (2,097.48 km) |
| La Crosse to Ionia (Michigan) | 314.35 mi (505.90 km) |
| La Crosse to Iowa City (Iowa) | 150.60 mi (242.36 km) |
| La Crosse to Irmo (South Carolina) | 859.83 mi (1,383.76 km) |
| La Crosse to Irondale (Alabama) | 751.45 mi (1,209.34 km) |
| La Crosse to Ironton (Ohio) | 575.07 mi (925.49 km) |
| La Crosse to Irvine (California) | 1,583.52 mi (2,548.43 km) |
| La Crosse to Irving (Texas) | 818.56 mi (1,317.35 km) |
