| La Crosse to Eugene (Oregon) | 1,576.68 mi (2,537.43 km) |
| La Crosse to Euless (Texas) | 821.31 mi (1,321.76 km) |
| La Crosse to Eureka (California) | 1,684.28 mi (2,710.59 km) |
| La Crosse to Eureka (Missouri) | 369.05 mi (593.94 km) |
| La Crosse to Eustis (Florida) | 1,160.84 mi (1,868.19 km) |
| La Crosse to Evans (Colorado) | 731.78 mi (1,177.69 km) |
| La Crosse to Evans (Georgia) | 860.85 mi (1,385.40 km) |
| La Crosse to Evanston (Illinois) | 216.80 mi (348.91 km) |
| La Crosse to Evanston (Wyoming) | 1,017.74 mi (1,637.89 km) |
| La Crosse to Evansville (Indiana) | 446.84 mi (719.12 km) |
| La Crosse to Everett (Massachusetts) | 1,019.58 mi (1,640.85 km) |
| La Crosse to Everett (Washington) | 1,504.50 mi (2,421.26 km) |
| La Crosse to Evergreen Park (Illinois) | 230.36 mi (370.72 km) |
| La Crosse to Ewa Beach (Hawaii) | 4,068.75 mi (6,548.02 km) |
| La Crosse to Ewa Gentry (Hawaii) | 4,068.98 mi (6,548.39 km) |
