| La Crosse to Elyria (Ohio) | 493.43 mi (794.09 km) |
| La Crosse to Emeryville (California) | 1,665.24 mi (2,679.95 km) |
| La Crosse to Emmaus (Pennsylvania) | 835.32 mi (1,344.31 km) |
| La Crosse to Emporia (Kansas) | 454.93 mi (732.14 km) |
| La Crosse to Encinitas (California) | 1,584.04 mi (2,549.27 km) |
| La Crosse to Endicott (New York) | 774.78 mi (1,246.89 km) |
| La Crosse to Endwell (New York) | 776.53 mi (1,249.70 km) |
| La Crosse to Englewood (Colorado) | 765.07 mi (1,231.27 km) |
| La Crosse to Englewood (Florida) | 1,265.27 mi (2,036.25 km) |
| La Crosse to Englewood (New Jersey) | 902.08 mi (1,451.76 km) |
| La Crosse to Englewood (Ohio) | 448.86 mi (722.37 km) |
| La Crosse to Enid (Oklahoma) | 620.72 mi (998.96 km) |
| La Crosse to Ennis (Texas) | 846.68 mi (1,362.60 km) |
| La Crosse to Ensley (Florida) | 943.93 mi (1,519.11 km) |
| La Crosse to Enterprise (Alabama) | 911.78 mi (1,467.37 km) |
